| Rotation | Assignment | Title/Topic Question |
| #2: Family Medicine | PICO 1 | In adults with new scaly skin plaques suspicious for psoriasis, does early dermatology referral compared with primary care management alone reduce time to accurate diagnosis and subsequent treatment? |
| #2: Family Medicine | PICO 2 | In patients with back pain secondary to strenuous activity, does treatment with muscle relaxants lead to better relief of symptoms compared to non-opioid analgesics (like Tylenol) or NSAIDs? |
| #2: Family Medicine | PICO 3 | In adults with new scaly skin plaques suspicious for psoriasis, does early dermatology referral compared with primary care management alone reduce time to accurate diagnosis and subsequent treatment? |
| #3: OBGYN | PICO 4 | In pregnant women with poorly controlled diabetes and a fetus diagnosed with congenital anomalies, does termination of pregnancy compared to continuation of pregnancy affect maternal morbidity and/or fetal/neonatal outcomes? |
| #3: OBGYN | PICO 5 | In post-op patients with sepsis and suspected pneumonia, does early initiation of broad spectrum antibiotics with MRSA and pseudomonas coverage compared to standard empiric therapy such as ceftriaxone and metronidazole reduce mortality and/or progression to septic shock? |
| #3: OBGYN | PICO 6 | In pregnant patients undergoing labor with planned vaginal delivery, does epidural anesthesia compared to no epidural anesthesia increase the likelihood of cesarean section? |
| Draft Mini-CAT | In adult patients with myasthenic crisis, does IVIG compared to plasmapheresis result in faster clinical improvement and reduced need for mechanical ventilation? | |
| Final Mini-CAT | In adult patients with myasthenic crisis, does IVIG compared to plasmapheresis result in faster clinical improvement and reduced need for mechanical ventilation? | |
| #5: Surgery | PICO 7 | In patients with anal fistulas, does seton placement compared with immediate definitive surgical repair without seton reduce postoperative complications and recurrence? |
| #5: Surgery | PICO 8 | In pregnant patients with high suspicion of acute appendicitis when US and MRI are unavailable, does CT imaging prior to surgery compared with immediate operative intervention reduce unnecessary appendectomies while maintaining favorable maternal and fetal outcomes? |

